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European Heart Journal Advance Access originally published online on May 19, 2008
European Heart Journal 2008 29(12):1478-1480; doi:10.1093/eurheartj/ehn226
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Mitral annular calcifications and aortic valve stenosis

M. Pachón and J. Zamorano*

Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain

* Corresponding author. Tel: +34 913303290, Fax: +34-91-3303292, Email: jlzamorano@vodafone.es

This editorial refers to ‘Association of mitral annular calcification and aortic valve morphology: a substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study’ {dagger} by D.S. Jassal et al., on page 1542

Footnotes

The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

{dagger} doi:10.1093/eurheartj/ehn172 Back

The first 10% of the full text of this article appears below.

Idiopathic mitral annular calcification (MAC) is one of the most common cardiac abnormalities found in autopsies, occurring twice as often in females than in males. It has been reported in 6.1% of the subjects that undergo a routine echocardiogram,1 and the incidence rises sharply with age. The primary pathological event in its development is considered to be a fibrillar alteration of the collagen ultrastructure that triggers lipid deposition and calcification within the annulus. Although it was initially thought that the presence of calcification of the mitral annulus had few functional consequences in most hearts, this is not the case. Patients with MAC have been shown to be at a higher risk of conduction disturbances, cardiovascular disease, and total cardiac death. Calcified . . . [Full Text of this Article]


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Related articles in EHJ:

Association of mitral annular calcification and aortic valve morphology: a substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study
Davinder S. Jassal, James W. Tam, Kapil M. Bhagirath, Isabelle Gaboury, Randall A. Sochowski, Jean G. Dumesnil, Peter J. Giannoccaro, John Jue, A. Shekhar Pandey, Campbell D. Joyner, Koon K. Teo, and Kwan L. Chan
EHJ 2008 29: 1542-1547. [Abstract] [Full Text]  

Association of mitral annular calcification and aortic valve morphology: a substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study
Davinder S. Jassal, James W. Tam, Kapil M. Bhagirath, Isabelle Gaboury, Randall A. Sochowski, Jean G. Dumesnil, Peter J. Giannoccaro, John Jue, A. Shekhar Pandey, Campbell D. Joyner, Koon K. Teo, and Kwan L. Chan
EHJ 2008 29: 1542-1547. [Abstract] [Full Text]